Phosphatidylserine (PS) and Age-Related Cognitive Decline (ARCD)

ثبت نشده
چکیده

1. Age-Related Cognitive Decline (ARCD) Age related cognitive decline (ARCD) [1] is the scientific term for memory loss in elderly people who are clinically healthy. It is a physiological process associated with aging, not a disease, and occurs during middle life or later. Many people who are clinically healthy find as they get into their forties or fifties, sometimes even as early as their thirties, that they are losing mental sharpness. They have more trouble to keep track of their glasses and their keys. They have increasing difficulties in remembering names and matching names to faces. After reading important material, they forget it within minutes. One estimates that more than 40 percent of people aged 50 to 59 show ARCD, as do more than 50 percent of people aged 60 to 69, and even a greater proportion of those past 80. The decline in memory is significant, approximately half of our memory capabilities at age 25 are lost at ages 50-59, and even up to three quarters at age 70+.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Age related cognitive decline: a clinical entity? A longitudinal study of cerebral blood flow and memory performance.

OBJECTIVES To evaluate the changes in regional cerebral blood flow (rCBF) and memory performance in patients with age related cognitive decline (ARCD) who did and did not become demented during a follow up period. METHODS Twenty four patients with ARCD were recruited from an outpatient memory clinic, of whom 18 were followed up over a mean period of two years. Eighteen patients with mild to m...

متن کامل

Dietary fatty acids, age-related cognitive decline, and mild cognitive impairment.

Currently available epidemiological evidence suggested that an increase of saturated fatty acids (SFA) could have negative effects on cognitive functions, while increased polyunsaturated fatty acids (PUFA) and monounsaturated fatty acids (MUFA) may be protective against cognitive decline. In a Southern Italian elderly population from the Italian Longitudinal Study on Aging (ILSA), a clear reduc...

متن کامل

The connection between MCI and Alzheimer disease: neurocognitive clues.

BACKGROUND/AIM Mild cognitive impairment (MCI) is defined as a pathological stage between 'healthy aging' and 'dementia' In this study, cases of MCI were compared with early-stage Alzheimer disease (AD) and age-related cognitive decline (ARCD) in terms of cognitive profiles in order to find a connection between MCI and AD. MATERIALS AND METHODS Patients who were comparable in terms of age and...

متن کامل

Mediterranean diet and cognitive decline.

OBJECTIVE To investigate the possible role of diet in age-related cognitive decline (ARCD) and cognitive impairment of both degenerative (Alzheimer's disease, AD) and vascular (vascular dementia, VaD) origin. DESIGN Literature review. RESULTS In an elderly population of southern Italy with a typical Mediterranean diet, high energy intake of monounsaturated fatty acids (MUFA) appeared to be ...

متن کامل

Vitamin E stimulates phosphatidylserine synthesis in the hippocampus and improves cognitive function at old age

Aged humans and animals demonstrate cognitive decline. Improvement of short-term memory performance in aged beagles with a nutraceutical supplement containing phosphatidylserine (PS) and vitamin E has been demonstrated. The purpose of the present study was to examine if alpha-tocopherol acetate could alter PS metabolism in the hippocampus and to improve cognitive function of aged rats. Intragas...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2007